Dị ứng cơ địa

Dị ứng cơ địa và những điều bạn nên biết về chứng bệnh

Dị ứng cơ địa là một trong những chứng bệnh gây nhiều khó chịu cho cơ thể. Vậy nguyên nhân dị ứng cơ địa, triệu chứng của chứng bệnh là gì? Dưới đây là một vài thông tin về chứng bệnh, các bạn cùng tham khảo nhé!

Dị ứng cơ địa và những điều bạn nên biết về chứng bệnh

1. Dị ứng cơ địa là gì? 

Dị ứng cơ địa có thể hiểu nôm na là từ lúc sinh ra cơ thể đã có “yếu tố” gây dị ứng, thường gặp khi thay đổi thời tiết, tiếp xúc với lông động vật nuôi như chó, mèo; hay do ăn uống như hải sản, đậu phộng… Việc điều trị dị ứng  da cơ địa chỉ giúp làm giảm mức độ ngứa và tần suất tái phát, chứ không khỏi hoàn toàn.

Điều đáng ngạc nhiên, cơ địa dị ứng có thể giảm dần hoặc khỏi hoàn toàn khi trưởng thành, sau khi sinh con (phụ nữ)…

Dị ứng cơ địa và những điều bạn nên biết về chứng bệnh
Dị ứng cơ địa và những điều bạn nên biết về chứng bệnh

2. Nguyên nhân dị ứng cơ địa

Dị ứng da cơ địa liên quan đến hệ thống miễn dịch trong cơ thể. Như chúng ta đã biết, hệ thống miễn dịch có nhiệm vụ bảo vệ và chống lại sự xâm nhập của những chất lạ (gọi là dị nguyên) vào cơ thể.

Do đó, mục tiêu của hệ miễn dịch là cố gắng phá hủy các dị nguyên tại vị trí chúng xâm nhập vào cơ thể. Một trong những nổ lực đó của hệ miễn dịch là tạo nên các protein bảo vệ được gọi là kháng thể để chống lại các dị nguyên này. Các kháng thể là những globulin miễn dịch – immunoglobulin (IgG, IgM, IgD, IgA) giúp bảo vệ và tiêu hủy các dị nguyên bằng cách bám vào bề mặt của chúng để tạo điều kiện cho các tế bào miễn dịch khác dễ dàng tiêu hủy. Ở những người bị dị ứng thì còn có sự sản xuất ra các globulin miễn dịch loại E (IgE) nhằm đáp ứng với các dị nguyên vô hại.

IgE là loại kháng thể mà tất cả chúng ta đều có với số lượng nhỏ. Tuy nhiên ở những người bị dị ứng thì IgE được sản xuất với số lượng lớn. Bình thường IgE giúp bảo vệ cơ thể chống lại các loại ký sinh trùng. Sự sản xuất quá mức của IgE sẽ kích thích sự phóng thích ra nhiều loại hóa chất, trong đó quan trọng nhất là chất histamine. Các hóa chất này (bao gồm histamine) sẽ gây nên hiện tượng viêm và các triệu chứng đặc hiệu của dị ứng.

Các nghiên cứu cho thấy, cơ địa dị ứng có tính chất di truyền rõ rệt, nếu cả bố và mẹ đều có cơ địa dị ứng thì các con của họ sẽ có 75% nguy cơ bị dị ứng. Nguy cơ này giảm xuống 50% nếu chỉ có bố hoặc mẹ bị dị ứng và 15% nếu cả bố và mẹ đều không bị dị ứng. 70% anh em sinh đôi cùng trứng có mắc các bệnh dị ứng giống nhau, trong khi sinh đôi khác trứng chỉ là 40%.

Thời gian gần đây, tỷ lệ mắc các rối loạn dị ứng gia tăng do nhiễm khuẩn và sử dụng kháng sinh trong giai đoạn đầu đời; ô nhiễm môi trường, tiếp xúc với dị nguyên, đặc biệt trong giai đoạn đầu đời; nhiễm giun, sán, kí sinh trùng và sự thay đổi chế độ ăn. Những trẻ em được nuôi hoàn toàn bằng sữa mẹ cũng có ít nguy cơ mắc các bệnh dị ứng hơn so với những trẻ được nuôi bằng sữa bột.

Các nghiên cứu dịch tễ học cũng cho thấy, trẻ em, đặc biệt là trẻ nam, có nguy cơ bị mắc các bệnh dị ứng cao hơn so với người lớn

3. Triệu chứng do dị ứng cơ địa gây ra

Các triệu chứng dị ứng cơ địa có thể xuất hiện tức thì trong vài giây đến vài phút sau khi tiếp xúc với dị nguyên, nhưng cũng có thể xuất hiện muộn sau vài ngày, thậm chí vài tuần. Biểu hiện và mức độ của các triệu chứng dị ứng ở mỗi cá thể tuỳ thuộc vào mức độ mẫn cảm của cơ thể, loại bệnh dị ứng mà cá thể đó mắc cũng như số lượng và cách tiếp xúc của dị nguyên gây bệnh.

Dị ứng cơ địa và những điều bạn nên biết về chứng bệnh
Triệu chứng của chứng bệnh viêm da cơ địa

Ví dụ, khi tiếp xúc với dị nguyên, người bệnh viêm mũi dị ứng thường có ngứa mũi, hắt hơi, chảy nước mũi và ngạt mũi; người bệnh hen phế quản lại biểu hiện các cơn khó thở, khò khè, thở rít, ho khạc đờm. Dị ứng do các dị nguyên đường ăn uống thường biểu hiện đau quặn bụng, buồn nôn, ỉa chảy, ngứa và nổi mề đay trên da…

Biểu hiện rõ ràng của dị ứng là viêm da cơ địa với các thương tổn da kèm theo ngứa, càng ngứa càng gãi nhiều, càng gãi lại càng có cảm giác ngứa nhiều hơn, chính vì mà da bị dày, bệnh nặng hơn và có nguy cơ bị bội nhiễm vi trùng. Bệnh viêm da cơ địa rất dễ tái phát đặc biệt là khi cơ thể tiếp xúc với các nguyên nhân gây bệnh;

4. Cách điều trị dị ứng cơ địa

Điều trị các bệnh dị ứng cơ địa nói chung có 3 vấn đề cơ bản là:

  • Tránh tiếp xúc với các dị nguyên gây bệnh
  • Sử dụng các thuốc chống dị ứng để giảm triệu chứng
  • Điều trị giảm mẫn cảm đặc hiệu khi xác định được tác nhân gây dị ứng.
  • Tránh tiếp xúc với dị nguyên là cách đơn giản và hiệu quả nhất để điều trị các bệnh dị ứng nhưng thường rất khó thực hiện trong thực tế. Việc loại bỏ hoàn toàn các dị nguyên vi thể trong không khí như bụi nhà, nấm mốc, phấn hoa gần như không thể. Nhưng giảm được số lượng các dị nguyên tiếp xúc trong môi trường sống và làm việc cũng có thể giúp cải thiện các triệu chứng dị ứng, giảm nhu cầu sử dụng thuốc chống dị ứng và cải thiện chất lượng cuộc sống.

Nói chung, cơ địa dị ứng thường tồn tại suốt đời nhưng các triệu chứng lại có thể thay đổi theo thời gian. Các bệnh dị ứng thường khởi phát ở trẻ nhỏ, ổn định dần ở tuổi dậy thì và tái phát lại sau đó, sớm hay muộn tuỳ thuộc vào môi trường sống và lối sống của mỗi cá thể.

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